Captain John McGinn could be out for up to two months in a further injury blow to Aston Villa.
The midfielder was forced off early in last week's defeat by Everton with a knee injury.
It means the Scotland international could miss up to nine games as third-placed Villa try to maintain their Premier League title push and Europe League hopes.
"Normally, he is going to be out for some weeks, maybe even one or two months. But I want to wait for the doctor's opinion on it," boss Unai Emery said.
McGinn's injury comes with Boubacar Kamara expected to miss the rest of the season with a serious knee injury he suffered in the FA Cup win at Tottenham this month.
Youri Tielemans also came off in Sunday's win at Newcastle leaving Villa with a midfield injury problem.
"It was his ankle. Hopefully not a lot, but we must check him with the doctor and wait. I can't say anything more," Emery added following the victory at St James’ Park.
Villa missed out on Conor Gallagher this month after the midfielder opted to join Tottenham from Atletico Madrid for £35m instead.
